RADIATION AND HYPOXIA STUDIES: EFFECTS OF HIGH-ENERGY ATMOSPHERIC PARTICLES ON BIOLOGICAL ORGANISMS AND POSSIBILITIES OF THEIR REHABILITATION KLYUCHKO O.M., LIZUNOV G.V., BELOSHITSKY P.V.

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ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)

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Biotechnologia Acta Т. 16, No. 6 , 2023
P. 48-68, Bibliography 105, Engl.
UDC: 612.233+612.176:577.151.6
DOI: https://doi.org/10.15407/biotech16.06.048

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RADIATION AND HYPOXIA STUDIES: EFFECTS OF HIGH-ENERGY ATMOSPHERIC PARTICLES ON BIOLOGICAL ORGANISMS AND POSSIBILITIES OF THEIR REHABILITATION

O.M. KLYUCHKO¹, G.V. LIZUNOV², P.V. BELOSHITSKY ³

¹National Aviation University, Educational & Research Institute of Air Navigation, Kyiv, Ukraine
² Space Research Institute of the National Academy of Sciences of Ukraine – State Space Agency of Ukraine, Kyiv
³P. Tychyny Uman State Pedagogical University, Ukraine

The influences of cosmic radiation on atoms and molecules in the Earth's atmosphere were observed with subsequent transformation of atoms, molecules of gases, as well as the development of states of oxygen deficiency (hypoxic) in biological organisms; some recommended ways of such disorders correction.
Aim.This work was purposed to study radiation effects in the ionosphere with subsequent high-energy transformations of atoms and molecules of gases at different heights above the Earth's surface, the interaction of some high-energy atmospheric particles with biological objects near Earth's heights up to 5.500 m above sea level (a.s.l.), and oxygen roles in consequences of biological organisms' irradiation.
Methods. Analysis of results of satellite and rocket observations of the Earth atmosphere gases exploring at different altitudes a.s.l. Investigations in mountain conditions at EMBS research station of the National Academy of Sciences of Ukraine: comparative analysis of results of long-term observation of patients using standard laboratory methods, complex of methodological techniques: clinical, physiological studies of respiratory, cardiovascular systems; hematological, immunological states; functional state of higher nervous activity, mental and neurotic state; antihypoxants use, histochemical, biophysical methods, math modeling, others.
Results.The last data obtained during the satellite atmosphere exploration were presented:

Studies of influences on the structure of atoms and molecules in the atmosphere
Concentrations of gases from the ionosphere to the Earth's surface
Such phenomena as photochemical processes and photoionization

The notion of "information" was discussed based on phenomena described in the article. Described studies of gas-particle modification and oxygen deficiency in organisms (hypoxic states) were supplemented with the results of irradiated Chornobyl patients' examinations and rehabilitation by Ukrainian doctors and scientists in mountain conditions.
Conclusions. Phenomena of solar radiation influence on atoms, molecules and molecular complexes in the Earth's atmosphere were observed. The primary attention was concentrated on the studies of gas concentrations at different heights with linked effects of oxygen roles in the consequences of organisms' irradiation and rehabilitation. Practical recommendations for patients' medical care and rehabilitation were made.

Key words: radiation damage of organisms, hypoxia, high altitudes, high-energy particles, free radicals.

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ORCID.:
KlyuchkoO- 0000-0003-4982-7490 ;
LizunovG- 0000-0002-4922-1248 ;
Beloshitsky Pavlo- 0000-0002-6058-3602.