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ISSN 1995-5537

"Biotechnology" journal V. 5, No. 2, 2012
Р. 9-30, Bibliography 140, Ukrainian.
Universal Decimal classification: 546.26.043

NANOBIOTECHNOLOGY: THE ROUTE TO NEW MICROWORLD
CREATED BY SYNTHESIS OF CHEMISTRY AND BIOLOGY

A. P. Demchenko V. I. Nazarenko

Palladian Institute of Biochemistry, Kyiv

The particles of 1–100 nm in size and the composites of molecules and these particles of inorganic, organic and biological nature possess unique properties that cannot be attributed to other materials. Their application induces revolutionary changes in existing technologies and creation of new technologies. In this review we analyze the properties of such nanocomposites in relation to their structure and also their versatile applications in biotechnology. We discuss different possibilities for research and development in industrial enzymology that appear due to inclusion of enzymes into nanostructures. Revolutionary new technologies came to the healthcare and brought generation of nanopharmacology and nanomedicine. Here, for the first time the possibilities appeared for controlled targeted delivery of drugs and their controlled release in target cells. We also discuss the prolem of patent protection of new ideas in this area. Expanded definition of nanotechnology is proposed.

Key words: nanobiotechnology, nanoparticles, self-assembly, nanocomposites, nanomaterials for medicine, nanoenzymology.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008