CELL TRANSPLANTATION IN THE CARDIOMYOPLASTY OF ISCHEMIC HEART INJURY A. K. Gulevsky, I. I. Schenyavsky, Ye. S. Abakumova

Details: Category: 1_2011(en); Hits: 177

ISSN 1995-5537

"Biotechnology" journal Vol. 4, No. 1, 2011
Р. 60-73, Bibliography 80, Russian.
Universal Decimal Classification: 576.371+615.361:616.12-005.8

CELL TRANSPLANTATION IN THE CARDIOMYOPLASTY
OF ISCHEMIC HEART INJURY

A. K. Gulevsky, I. I. Schenyavsky, Ye. S. Abakumova

Institute for Problems of Cryobiology and Cryomedicine
of National Academy of Sciences of Ukraine, Kharkіv

In the review the data on the use of cellular therapy for reparative regeneration of myocardium after ischemic injury are presented. The regenerative potential of cardiac muscle by means of its own progenitor cells of cardiomyocytes as well as the prospects of cell therapy by transplantation of embryonic stem cells, mononuclear fraction of bone marrow hematopoietic stem cells, fetal and neonatal cardiomyocytes and by implantation into the region of damaged muscle cells and purified myoblasts satellites are summarized. Availability of creating of the stem cells cryobanks for cardiomyoplasty at acute myocardial infarction is proved.

Key words: reparative regeneration of myocardium, myocardial infarction, cell therapy, stem cells, stem cell cryobank.