ISSN 1995-5537
"Biotechnology" journal Vol. 2, No. 3, 2009
Р. 44-54, Bibliography 101, Ukrainian.
Universal Decimal classification 612.393:577.151.6+547.972
Bremen, Germany
Some structural pecularities of soybean isoflavones determine their biological activity: antioxidant, inhibitory, weak estrogenic and antiestrogenic (because of similarity with estrogen hormones). Isoflavones are nontoxic, soy is used as a component of commercial infant dietes. High consumption of soy in Japan and China is a reason of low cardiovascular and oncologic pathology. Antioxidant and estrogenic effects of isoflavones provide normalization of cholesterol, triglyceride level, lipoprotein peroxidation, normalization of lipid metabolism. Inhibiting action of ispoflavone on tyrosinkinase, topoisomerase, ornitindecarboxilase activity, antiproliferative effect limit the induction and development of some tumors, especially hormonodependent.
Key words: soybean isoflavones, biological activity, practical application.
© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008