ISSN 1995-5537

"Biotechnology" journal Vol. 2, No. 2, 2009
Р. 9-22, Bibliography 95, Russian.
Universal Decimal classification: 615.37: 615.246.2

IMMUNOADSORРTION FOR THERAPY OF AUTOIMMUNE DISEASES

 K. I. Bardakhivska, N. M. Gurina, T. M. Kuchmerovska, V. G. Nikolaev

R. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology
National Academy of Sciences of Ukraine, Kyiv
O. V.Palladin Institute of Biochemistry
National Academy of Sciences of Ukraine, Kyiv

 In review, application of immunoadsorption for therapy of autoimmune diseases is elucidated. It was focused on the most widespread autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis and other. Current knowledge concerning pathogenesis of autoimmune diseases was also covered. Treatment of these diseases due to coplexity of the underlying mechanisms requires new approaches besides using traditional therapy. Growing evidence suggests that such approaches may include immunoadsorption. It was demonstrated that immunoadsorption may be applied as main or additive method in combined therapy of autoimmune diseases due to its high efficacy and safety.

 Key words: immunoadsorbtion, immunosorbent, autoimmune diseases.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008I