ISSN 1995-5537
"Biotechnology" journal Vol. 2, No. 1, 2009
Р. 46-58, Bibliography 88, English.
Universal Decimal classification 547.9:612.397:678.012
DIRECTED DRUG DELIVERY SYSTEMS. BIOTECHNOLOGICAL ASPECTS
O. Yu. Galkin, L. B. Bondarenko, A. S. Grishyna, O. M. Dugan
National Technical University of Ukraine «Kiev Polytechnic Institute», Kyiv
Institute of Pharmacology and Toxicology of AMS of Ukraine, Kyiv
Publications concerning methods of creation of the drug delivery systems based on liposomal forms and receptordependent endocytosis are summarized. The methods of use of the directed drug delivery systems in creation of anticancerogenical and antibacterial agents, vaccines and in gene therapy are examined.
Key words: directed drug delivery systems, pharmaceuticals, liposomes, endocytosis, anticancer agents, monoclonal antibodies.