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ISSN 1995-5537

4 2008

"Biotechnology" journal Vol. 1, No. 4, 2008
Р. 9-17, Bibliography 48, Ukrainian.
Universal Decimal classification 577.15

 
Palladin Institutе of Biochemistry of National Academy of Sciences of Ukraine, Kyiv
Taras Schevchenko Kyiv National University
 

Protein C pathway is an important link in numerous physiological and pathophysiological processes of organism. The particular features of protein C structure and mechanisms of its activation are considered. Special attention is given to functioning of activated protein C, to its anticoagulant, antiinflammatory and profibrinolytical properties. Possible therapeutic application of protein C for the treatment of large number of pathologies characterized by protein C deficiency is observed. Current sources and approaches for protein C preparation are described.

Key words: protein C, hemostasis, anticoagulant, inflammation.
 

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008