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ISSN 1995-5537

2 2008

“Biotechnology” journal Vol. 1, No. 2, 2008
P. 13-23, Bibliography. 71, Russian
Universal Decimal classification: 577.122.5

ON SOME PECULIARITIES OF TRANSGENIC PROTEINS’ STRUCTURE FORMATION AND CONNECTED RISK FACTORS

S. V. Verevka

Academy of Medical Sciences of Ukraine
Kolomiychenko Institute of Otolaringology
Palladin Institute of Biochemistry of Nаtional Academy of Ukraine, Kyiv

The problems created by the development of transgenic food technologies are under consideration. Generalization of the data on the molecular mechanisms of the protein structure formation and processing allowed to base the principle of the correlative action of the structure forming, structure keeping and protein eliminating systems. The ways of the possible disturbances of such inter protein coordination by transgenic proteins as well as their possible consequences are discussed.

Key words: transgenic proteins, risk factors, chaperones, misfolding, prions.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008