ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)
"Biotechnologia Acta" V. 8, No 4, 2015
https://doi.org/10.15407/biotech8.04.108
Р. 108-112, Bibliography 33, English
Universal Decimal Classification: [546.264+615.277.3]:595.799
EFFECTS OF C60 FULLERENE — CISPLATIN COMPLEX ON
HONEYBEE Apis mellifera L.
Kuznietsova H. M.1, Ogloblya O. V.1, Cherepanov V. V.2, Prylutskyy Yu. I.1, Rybalchenko V. K.1
1Taras Shevchenko National University of Kyiv, Ukraine
2Institute of Physics of the National Academy of Sciences of Ukraine, Kiyv
The toxicity of С60 fullerene, traditional cytostatic cisplatin and С60 fullerene-cisplatin complex on honeybee Apis mellifera L. toxicity estimation test system was assessed. Water-soluble pristine C60 fullerenes were nontoxic for honeybee when consumed with the food in doses equivalent nontoxic and effective ones for mammalian. Cisplatin toxicity for honeybee in the doses exceed the same for mammalian in 2 times was observed as fallows: honeybee 56% death occurred after consumption of 60 mg/kg of bee weight. С60 fullerene-cisplatin complex proved to be more toxic for honeybee in comparison with free cisplatin and caused honeybee 50% lethality after consumption of 40 mg/kg bee weight.
Key words: C60 fullerene, cisplatin, honeybee.
© Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, 2015
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