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ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)

1 2013

"Biotechnologia Acta" v. 6, no. 1, 2013 10.15407/biotech6.01.062
Р. 62-72, Bibliography 67, Russian.
Universal Decimal classification: 577.083.3+612.017.1.08


M. T. Tagirov

Poultry Research Institute of the National Academy
of Agrarian Sciences of Ukraine, Borki of Kharkiv Region

The modern conception of genetic bases of bird’s sex determination is considered. Following the genotypic mechanism of sex determination, birds implement a complex system of sex chromosome relationships. Z chromosome contains a dose-dependent male sex determinant — gene DMTR1 ensuring the testicles development upon two copy availability in the ZZ combination. Some factors on the W hromosome are not yet identified. On the one hand, they suppress the activity of the DMTR1 gene and on the other hand they activate aromatase enzyme, which in ZW combination  promotes the female sex development. It was suggested that while a number of different classes of animal adaptations are appeared ensuring stable embryo development, the dependence of sex determination upon environment and inner signals at the later stages of embryogenesis is reduced. At the same time, sex determinants fixed on genetic level are appeared that are active at the very early stages of development.

Key words: bird, sex determination, sex chromosomes, sex inversion, meiotic drive, gonads.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008