ISSN 1995-5537
"Biotechnology" journal Vol. 1, No. 4, 2008
Р. 39-48, Bibliography 30, Russian.
Universal Decimal classification 611.018.26.013
Institute for problems of cryobiology and cryomedicine of the National Academy of Scienses of Ukraine, Kharkiv
Due to ability to differentiation into different cells of connective tissue mesenchymal stem cells (MSC) are promising object for biotechnology and regenerative medicine. The most studies on human MSC have been carried out on cells isolated from adult bone marrow. In stromal fraction of adipose tissue the cell population with multilineage differentiation potential has been revealed. The aim of the review is to describe the current state of isolation method and properties of MSC from adipose tissue. Stromal cells from adipose tissue possess of similar to bone marrow derived MSC immunophenotype and capacity to multilineage differentiation. At once some peculiar properties of MSC isolated from these sources are discussed.
Key words: stem cells, adipose tissue, immunopheno type, differentiation potential, bone marrow.
© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008