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ISSN 1995-5537

2 2008


“Biotechnology” journal Vol. 1, No. 2, 2008
Р. 99-103, Bibliography 11, Ukrainian.
Universal Decimal classification 577.213.3

Institute of Molecular Biology and Genetics of National Academy of Sciences of Ukraine
Diagnostic methods for mutant variants detection of some exons in PAH gene (phenylketonuria) and CFTR gene (cystic fibrosis) using denaturing gradient gel-electrophoresis (DGGE) were developed. High effectiveness method for the application in the screening programs of these severe hereditary diseases among the population of Ukraine was shown.

Key words: DGGE, gene, mutations, DNA diagnostics, phenylketonuria, cystic fibrosis.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008