ISSN 1995-5537
“Biotechnology” journal Vol. 1, No. 2, 2008
Р. 93-98, Bibliography 15, Ukrainian.
Universal Decimal classification 573.086.83.002.56
Taras Shevchenko Kyiv National University
Laboratory for the quality control of med ical drugs
Laboratory for the quality control of med ical drugs
TOV «International United Laboratory Group», Kyiv
Palladin Institute of Biochemistry of the National Academy of Sciences, Kyiv
Palladin Institute of Biochemistry of the National Academy of Sciences, Kyiv
The condition of the quality control of combined medical drugs with different active components was developed. Identification of active components as well as determination of its quantity is important for the quality control. The effective method of the quality control of combined medical drugs was developed using high-performance liquid chromatography. This method was applied for identification of the levodopa and carbidopa which have similar chemical structure as well as impurities (tyrosine). The method was included into the analytical normative documentation for the quality control of combined medical drugs during manufacturing and storage.
Key words: hidh performance lignia chromatography, levadopa, carbidopa, quality control.
© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008
© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008