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ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)

 2 2014

"Biotechnologia Acta" v. 7, no 2, 2014
Р. 9-25, Bibliography 179, Ukrainian.
Universal Decimal classification: 759.873.088.5:661.185


T. P. Pirog, A. D. Konon, A. P. Sofilkanich

National University of Food Technologies, Kyiv, Ukraine

The classification and the chemical structure of the lipopeptides and their producers (bacteria of the genera Bacillus and Pseudomonas) are given. The role of the lipopeptides in cells motility, biofilm formation, metal binding and xenobiotics degradation and their action on the cells of pro- and eukaryotes is summarized. The stages of the nonribosomal lipopeptides synthesis and the role of two-component (GacA/GacS, ComA/ComP) and the quorum system regulation of this process are shown.

The potential of lactic acid bacteria and marine microorganisms as alternative surfactants producers (glycolipids, lipopeptides, phospholipids and fatty acids, glycolipopeptides) are discussed. Their productivity and advantages over traditional producers are given as well. The properties of surfactants synthesized by lactic acid bacteria (the reduction of the surface tension, the critical micelle concentration, the stability in a wide range of pH, the temperature, the biological activity) are  summarized.

Surfactants of nonpathogenic probiotic bacteria could be used as effective antimicrobial agents and antiadhesive and marine producers which able to synthesize unique metabolites that are not produced by other microorganisms.

Key words: microbial surfactants, lipopeptides, lactic acid bacteria, alternative producers.

© Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, 2014


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