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ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)

 1 2014

"Biotechnologia Acta" v. 7, no 1, 2014
https://doi.org/10.15407/biotech7.01.123
Р. 123-130, Bibliography 26, Russian
Universal Decimal classification: 547.953:615.012:665:372

HEPATOPROTECTIVE ACTION OF BIOPREPARATIONS FROM DEFATTED SOY AND SUNFLOWER LECITHINS

Drozdov O. L.1, Shulga S. M.2, Adab M.1, Glukh I. S.2

1Research Institute of Medical and Biological Problems of SE «DMA» Ministry of Health, Dnіpropetrovsk
2State Organization «Institute of Food Biotechnology and Genomic»
of National Academy of Sciences of Ukraine, Kiyv

The results of studies of hepatoprotective activity of biopreparations of defatted soy and sunflower lecithins under carbon tetrachloride intoxication of the experimental animals are given. Analyze of biochemical and histological data under soy and sunflower lecithin exposure changed in terms of poisoning enables to conclude that both biological products of defatted lecithin slowed the growth of mass of animal liver and transaminase activity and stimulated liver regeneration as a result of polyploidy and hypertrophy of hepatocytes, resuscitated beam and lobulation organ and created contacts between hepatocytes and venous vessels as well. It is evidenced that repair processes are activated in condition of their injection under carbon tetrachloride intoxication.

Key words: lecithin, tetrachloromethane, hepatoprotectors.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2014

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