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ISSN 1995-5537

4 2011

"Biotechnology" journal V. 4, No. 4, 2011
Р. 50-58, Bibliography 27, Ukrainian.
Universal Decimal classification: 577.118:636.4

METABOLIC INDICES OF PIGLETS BLOOD AT FEEDING OF CULTURAL LIQUID OF THE YEAST Saccharomyces cerevisiae CONTAINING CHROMIUM BIOCOMPLEXES

R. Ya. Iskra, M. V. Gonchar, H. I. Nechay, I. Ya. Maksymovych

Institute of Animal Biology of the National Academy of Agricultural Sciences of Ukraine, Lviv
Institute of Cell Biology of the National Academy of Sciences of Ukraine, Lviv
Branch Campus of the Faculty of Biotechnology, Rzeszow University, Kolbuszowa, Poland

In natural environment chrome is mainly in two valency states: six- (chomates and bichromates) and trivalent (Cr3+ compounds). Chromates are widely used in industry, in the process of steel production, cast-iron alloys, treatment of wood and leather tanning. There is a lot of information about toxic, mutagenic and carcinogenic action of Cr(VI).

The effect of chromium in cultural liquid of the yeast Sacharomices cerevisiae on protein and carbohydrate metabolisms as well as a system of antioxidant protection in piglets’ blood after weaning was investigated. It was found that culture liquid addition to the piglets diet containing biocomplexes of chromium led to reduction of urea and glucose in blood plasma, increase of total protein, activity of enzymes lactate dehydrogenase, catalase and glutathione peroxidase and reduced glutathione content in erythrocytes of blood.

No significant differences between animal parameters that were fed culture — liquid of the yeast containing Cr(III) in the form of synthesized biocomplexes and one containing chromium as chelant were found.

Key words: piglets, yeast, chromium, protein­, lactate dehydrogenase, antioxidant protection enzymes.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008