Biotechnologia Acta


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General information

Results of scientific research and survey on different directions of current biotechnology, short communications, articles on biotechnology history, and new publications on biotechnology and adjoining branches of science are published in English and have identical summaries in Ukrainian and Russian languages.

Authors are strongly encouraged to submit manuscripts online.

Article submission and editorial prpocessing is free of charge.

Unsure if your paper is suitable for Biotechnologia Acta. Send us a presubmission inquiry at This e-mail address is being protected from spambots. You need JavaScript enabled to view it , and we'll let you know what we think in 2–5 business days. Please include a title, an abstract, and an explanation of why your paper is significant and broadly interesting.

Our authorship policy accommodates diverse types of research, providing a framework that makes clear the contributions of each author.

Author Contributions Section: To make author contributions transparent, all research articles should include an Author Contributions section. Please describe the contributions concisely and use initials to indicate author identity.
An Authors Contributions section is not required for front-matter articles.

Corresponding Author and Lead Contact: You must designate at least one corresponding author and only one lead contact.

Corresponding Author: We prefer that each paper have a single corresponding author because we think that the ownership and responsibility that are inherent in corresponding authorship will promote best practices in design and performance of experiments, analysis of results, organization and retention of original data, and preparation of figures and text.

That said, we understand that, for some studies, particularly for interdisciplinary ones, multiple authors may bear the responsibilities of a corresponding author. If you feel strongly and have compelling reasons, you may include additional corresponding authors. We may ask you to explain your rationale and to verify that all corresponding authors understand their responsibilities (listed below). We ask that you describe each corresponding author's specific contributions in the Author Contributions section.

Lead Contact: The lead contact is the corresponding author who is also responsible for communicating with the journal (before and after publication) and accountable for fulfilling requests for reagents and resources and for arbitrating decisions and disputes. For research papers with multiple corresponding authors, please designate one (and only one) corresponding author as the lead contact. If there is only one corresponding author, then that author is automatically also the lead contact. You should denote the lead contact with a footnote in the author list (e.g., "5Lead Contact").

Responsibilities of the Corresponding Author and Lead Contact: All corresponding authors bear responsibilities 1–8 below; the lead contact additionally bears responsibility 9.
1.    Supervising the work
2.    Being responsible for all data, figures, and text
3.    Ensuring that authorship is granted appropriately to contributors
4.    Ensuring that all authors approve the content and submission of the paper
5.    Ensuring adherence to all editorial and submission policies
6.    Identifying and declaring conflicts of interest on behalf of all authors
7.    Identifying and disclosing related work by any co-authors under consideration elsewhere
8.    Archiving unprocessed data and ensuring that figures accurately present the original data (see Data Archiving section)
9.    Communicating with the journal (before and after publication), being accountable for fulfilling requests for reagents and resources, and arbitrating decisions and disputes

Equal Contributions: The lead contact is the only designation that we strictly limit to one author. In addition to noting corresponding authors with an asterisk, you may use numbered footnotes to designate senior authors and otherwise equally contributing authors. The following footnote should be used for authors who have made equal contributions: “6These authors contributed equally”. Senior authors can be designated with a footnote, e.g., “6Senior author”. Please use the Author Contributions section of the manuscript to more fully describe each author’s specific contributions.  
Authorship Disputes: All authors should discuss and agree on author order and authorship designations. We expect that everyone listed as an author contributed substantively to the paper.
We do not adjudicate authorship disputes. These disputes should be resolved by the researchers involved and/or their institutions. If we become aware of a dispute we will suspend consideration of the paper until the dispute is resolved. In this case (and when authors request changes to authorship) authorship should be approved in writing by all authors.

Bioethical norms

“Biotechnologia Acta” is focuses on the rules recommended by the European Convention for the Protection of Vertebrate Animals used for Experimental and Other Scientific Purposes (Strasbourg, 1986) and International Committee of Medical Journal Editors (ICMJE).

All procedures describing experiments involving laboratory animals, any biomaterials of human origin including donors and/or patients should be carried out guided by the bioethics norms. Experimental record should be reviewed and approved by the National Commissions on Bioethics and meet the International Standards.

If doubt exists whether the research was conducted in accordance with the 1964 Helsinki Declaration or comparable standards, the authors must explain the reasons for their approach, and demonstrate that the independent ethics committee or institutional review board explicitly approved the doubtful aspects of the study.

The following statements should be included in the text before the References section:
In case of ethical approval  it should be the following atatement^”All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.” For retrospective studies formal consent is not required.
2) Statement on the Welfare of Animals
The welfare of animals used for research must be respected. When reporting experiments on animals, authors should indicate whether the international, national, and/or institutional guidelines for the care and use of animals have been followed, and that the studies have been approved by a research ethics committee at the institution or practice at which the studies were conducted (where such a committee exists).
For studies with animals, the following statement should be included in the text before the References section:
In case of ethical approval  it should be the following atatement^” All applicable international, national, and/or institutional guidelines for the care and use of animals were followe”. If applicable (where such a committee exists) the statement should be as follows^ “All procedures performed in studies involving animals were in accordance with the ethical standards of the institution or practice at which the studies were conducted.”
If articles do not contain studies with human participants or animals by any of the authors, please select one of the following statement:» This article does not contain any studies with human or animals participants performed by any of the authors.”

Basic requirements to the articles are novelty, relevance and validity of the given facts, reproducibility of the experimental data on the reported methods and drawing up of the manuscript according to the journal requirements. Citations to unpublished data and personal communications cannot be used to support significant claims in the paper. Papers will be held for publication until all “in press” citations are published.

Article submission

Submission of a manuscript implies: that the work described has not been published before; that it is not under consideration for publication anywhere else; that its publication has been approved by all co-authors, if any, as well as by the responsible authorities – tacitly or explicitly – at the institute where the work has been carried out. The publisher will not be held legally responsible should there be any claims for compensation.

Authors wishing to include figures, tables, or text passages that have already been published elsewhere are required to obtain permission from the copyright owner(s) for both the print and online format and to include evidence that such permission has been granted when submitting their papers. Any material received without such evidence will be assumed to originate from the authors.

The following documents are provided via E-mail This e-mail address is being protected from spambots. You need JavaScript enabled to view it :
•    full text of the article (including a summary in three languages, tables, figures and their captions placed as mentioned in the text and a list of references as well). This file should be named after the first author (family_name.doc);
•    color illustrations;
•    full names, first names and patronymics of all authors and full postal addresses of their institution should be given, including post codes, in Ukrainian, Russian, and English languages. The corresponding author/s should be indicated, including their e-mail and telephone;
•    copyright contract signed by all authors (see the Licennse Agreement on the Journal site). No part of the Journal publications may be reproduced, stored in a retrieval system or transmitted in any form without the prior permission of the publisher. If the Editorial Board rejects the article the Licennse Agreement automatically loses its force. Signing the Licennse Agreement by the authors means that they are familiar and agree with the terms of the contract.

General requirements to manuscript

The editors reserve the right to return the manuscripts that are not in accordance with the following instruction

The date of the paper receipt is the date of arrival of its last, correct version to the editorial office.

The materials should be submitted in the Microsoft Word-supported format, page size of A4, book-oriented, font Times New Roman, at 14 point size, of one and a half spacing.

The manuscript (including tables, list of references, figures, and figure captions) should not exceed 30 pages (60 thousand symbols) for review articles, 20 pages (40 thousand symbols) for experimental one, 8 pages for short reports, 5–6 pages for current events and reviews. Figure volume is 1/4 of the article. Pages should be numbered consecutively, including tables, references, figure captions, summaries, etc. All tables, figures and their captions should have a concise title and serial number. The notes on the table are placed straight under the table. Footnotes can be used to explain abbreviations.

Figures should be in one of the electronic formats * jpg or *tif in in color.

The articles are reviewed - single-blind peer review - by two independent experts who are appointed by the Editorial Board and do not have conflicts of interest with the authors.

Section article

Experimental articles should have the following scheme:
•    Title page;
•    Structured abstracts;
•    Text of the article;
•    Acknowledgements (where applicable);
•    Data concerning financial support (where applicable);
•    References.

Title page:
•    UDC (Universal Decimal Classification);
•    article title;
•    full names of all the authors;
•    name and postal address of the institution which each author works in;
•    e-mail of the corresponding author.

Article title should be brief (not more than 8-10 significant words), informative, contain keywords and cover adequately the content of the article.

Names of all authors should be given in full. Each author should list an associated department, university, or organizational affiliation and its location, including city, state/province (if applicable), and country.

Name of the institution: If there are some authors and they work in different institutions, it needs to show in Arabic (indices) the names of the authors of the appropriate institutions.

Structured abstracts:

Abstracts up to 1,500 characters with spaces should contain:
•    article title;
•    names of all authors;
•    text of the abstract for experimental articles should be carefully structured and contain the following sections: aim, methods, results, conclusion;
•    keywords (not more than ten).

In addition, an abstract should:
•    explain how the study was done which includes any model and organisms were used, without getting into methodological specifics;
•    summarize the most important results and their significance.

Abstracts should not include:
•    citations;
•    abbreviations.

Text of the article
Experimental articles should have the following sections (headlines):
•    introduction (not entitled),
•    materials and methods,
•    results and discussion,
•    conclusion (not entitled)
•    acknowledgements
•    reference list

State the objectives of the work and provide adequate background, avoiding a detailed literature survey or a summary of the results.The relevance and purpose of the study is formulated in the introduction.

Materials and Methods
Provide sufficient details to allow the work to be reproduced. Methods already published should be indicated by a reference. Only relevant modifications should be described.

Results should be clear and concise and describe the outcome of the study. Data should be presented as concisely as possible, if appropriate in the form of tables or figures, although very large tables should be avoided.


All tables are to be numbered using Arabic numerals.

Tables should always be cited in text in consecutive numerical order.

For each table, please supply a table caption (title) explaining the components of the table.

Identify any previously published material by giving the original source in the form of a reference at the end of the table caption.

Footnotes to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data) and included beneath the table body.

Figure Numbering
All figures are to be numbered using Arabic numerals.
Figures should always be cited in text in consecutive numerical order.
Figure parts should be denoted by lowercase letters (a, b, c, etc.).
If an appendix appears in your article and it contains one or more figures, continue the consecutive numbering of the main text. Do not number the appendix figures,

"A1, A2, A3, etc." Figures in online appendices (Electronic Supplementary Material) should, however, be numbered separately.

Figure Captions
Each figure should have a concise caption describing accurately what the figure depicts. Include the captions in the text file of the manuscript, not in the figure file.
Figure captions begin with the term Fig. in bold type, followed by the figure number, also in bold type.
No punctuation is to be included after the number, nor is any punctuation to be placed at the end of the caption.
Identify all elements found in the figure in the figure caption; and use boxes, circles, etc., as coordinate points in graphs.
Identify previously published material by giving the original source in the form of a reference citation at the end of the figure caption.

Figure Placement and Size
Figures should be submitted separately from the text, if possible.
When preparing your figures, size figures to fit in the column width.

This section should highlight the significance and novelty of the presented results. A combined Results and Discussion section is often appropriate. Avoid extensive citations and discussion of published literature.

The list of references should only include works that are cited in the text and that have been published or accepted for publication. Personal communications and unpublished works should only be mentioned in the text. Do not use footnotes or endnotes as a substitute for a reference list.

|On the common techniques it is enough to give references to publications. All the designations and denominations of physical units should be given in SI International System. Amino acids are indicated by abbreviated symbols of three letters or in single letter format FASTA.

Names of the enzymes and their codes should be given according to the recommendations of the International Biochemical Society (Enzyme Nomenclature – Acad. Press. San Diego. California and Supplement (1-6) in Eur. J. Biochem. (1993-1997, 1999) or electron version:

Names of companies and countries producers of the reagents and materials used in the experiments should be given. The number and species of the used animals as well as the methods of anaesthetization and euthanasia should be defined.

Authors should describe statistical methods with enough detail to enable a knowledgeable reader with access to the original data to verify the results. All quantitative data require statistical analysis. Its results should be given in the tables and figures. Data validity is shown as follows: * — P ≤0.05.

Latin name of the genus and species of the organisms should be given in italics. Mentioning firstly, it is given full specific name (preferably with indication of taxon author), and subsequently the name of the genus could be given shortly with one letter, unless it concerns species belonging to different genera with the same first letter. Latin names of taxons are given according to current sources. It needs to use only standard abbreviations of names for measures, physical, chemical and mathematical variables and terms, all other abbreviations have to be interpreted.

If materials, methods, and protocols are well established, authors may cite articles where those protocols are described in detail, but the submission should include sufficient information to be understood independent of these references.

Only published or accepted manuscripts should be included in the reference list. Manuscripts that have been submitted but not yet accepted should not be cited. References must be listed at the end of the manuscript and numbered in the order that they appear in the text. In the text, citations should be indicated by the reference number in square brackets.

The authors are responsible for the correctness of the original sources.

Citation of published and readily accessible materials to readers is only available: articles, books, conference proceedings, dissertations, patents.

It is desirable that the manuscript has no more than 20 references in experimental work, 100 references in review, and refer to recent years.

Editorial staff has no responsibility for correctness and completeness of the given bibliographic data.

Recommendations of the "Biotechnologia Acta" journal for the references compilation:

Published papers:

Narezhnaya E. V., Askalepova O. I., Nikashina A. A. Krukier I. I., Pogorelova T. N. Determination of L-arginine in amniotic fluid by capillary disk electrophoresis. Zhurnal Anal. Khim. 2010, 65(12), 1309–1312. (In Russian).

Liang G., Klose R. J., Gardner K. E., Zhang Y. Yeast Jhd2p is a histone H3 Lys4 trimethyl demethylase. Nature Struct. Mol. Biol. 2007, 14(2), 243-245.

Rodrigues L. R. Inhibition of bacterial adhesion on medical devices. Adv. Exp. Med. Biol. 2011, V. 715, Р. 351–367.

Skochko A.B., Konon A.D., Pirog T.P. Research of antiadhesion properties of surface-active substances of Аcinetobacter calcoaceticus IMV В-7241. Kharchova promislovist. 2012, N13, P. 77–80. (In Ukrainian).

Examples of paper descriptions with DOI:
Yang S. Y., Ryu I., Kim H. Y., Kim J. K., Jang S. K., Russell T. P. Nanoporous membranes with ultrahigh selectivity and flux for the filtration of viruses. Advanced Materials. 2006, 18(6), 709–712.

Riabinina A. A., Berezina E. V., Usol'tseva N. V. Surface Tension and Lyotropic Mesomorphism in Systems Consisting of Nonionogenic Surfactant and Water. Lyotropic Liquid Crystals and Nanomaterials: Proceedings of the Seventh International Conference. Ivanovo: Ivanovskii Gos. Univ. 2009. (In Russian).

Kordyum V., Suhorada E., Ruban T. Informational conditioning as the mechanism of permanent organism reconstruction. Abstracts of the 1st World Congress of Regenerative Medicine, Leipzig, Germany. 22–24 October 2003.

Electronic journal articles:
Hindorff, L. A. (all authors) A Catalog of Published Genome-Wide Association Studies. Available at (accessed, September, 2012).

Description of the electronic encyclopedia articles:
Containerization. (2008). In Encyclop?dia Britannica. Retrieved May 6, 2008, from

Links to Web resources:
Pravila Tsitirovaniya Istochnikov (Rules for the Citing of Sources) Available at: (accessed 7 February 2011).

Links to online resource of scientific and technical reports:
Deming D, Dynarski S. The lengthening of childhood. (NBER Working Paper 14124). Cambridge, MA: National Bureau of Economic Research. Retrieved July 21, 2008, from

McCartney E.J. Optics of the atmosphere. N. Y.: Willey. 1977, 400 p.

Book chapter:
Trachtenberg I. M., Levitsky E. L. Genetic toxicology. Genetic medicine. Zaporojan S.B. (Ed.). Odessa State University. 2008, P. 183–221. (In Russian).
6 p.

Lugovskoy E. V. The Molecular Mechanisms of Fibrin Formation and Fibrinolysis. Kyiv: Naukova Dumka. 2003. 219 p. (In Russian)

Dissertation abstracts:
N. Kawasaki. Parametric study of thermal and chemical nonequilibrium nozzle flow. M.S. thesis, Dept. Electron. Eng., Osaka Univ., Osaka, Japan. 2003.

J. O. Williams. Narrow-band analyzer. Ph.D. dissertation, Dept. Elect. Eng., Harvard Univ., Cambridge. MA. 2010.

Young R. F. Crossing boundaries in urban ecology: Pathways to sustainable cities (Doctoral dissertation). Available from ProQuest Dissertations & Theses database. 2007. (UMI No. 327681).

Encyclopaedia, dictionary:
Sadie S., Tyrrell J. (Eds.). The new Grove dictionary of music and musicians (2nd ed., Vols. 1-29). New York, NY: Grove.

Wilkinson J. P. (all the authors). Nonlinear resonant circuit devices. U.S. Patent 3 624 125. July 16, 1990.
NOTE: Use “issued date” if several dates are given.

Short messages
Smaller articles by volume that have an implicit novelty and relevance for biotechnology are published in “Biotechnologia Acta” journal. These articles are intended to present new information of exceptional novelty, importance and interest to the broad readership of the journal and are passed expedite reviewing and published in a short time. The total volume of a short message is limited to 10 typewritten pages, number of drawings and/or tables should not exceed 3, and a list of used literature sources should not contain more than 15.

Sections of the short messages are similar to that of the original article but are not shown with headings and subheadings, the results could be given together with the discussion.

Author for correspondence should justify the expediency of such an extraordinary publication in a letter to the editor. In case of acceptance, such work could be published within 3–4 months.


Authors can correct only found mistakes in the made up pages without making additional changes and supplements.Giving an article to “Biotechnologia Acta” journal, an author thereby deligates the rights to the Publisher (©Palladian Institute of Biochemistry of National Academy of Sciences of Ukraine) to edit, translate into any language, reproduce and publish the work in form and format adopted by the editor.

Copyright Permission Policy
These guidelines apply to the reuse of articles, figures, charts and photos in the Biotechnologia Acta journal.

For authors reusing their own material:
Authors need NOT contact the journal to obtain rights to reuse their own material. They are automatically granted permission to do the following:
- Reuse the article in print collections of their own writing.
- Present a work orally in its entirety.
- Use an article in a thesis and/or dissertation.
- Reproduce an article for use in the author's courses. (If the author is employed by an academic institution, that institution also may reproduce the article for teaching purposes.)
- Reuse a figure, photo and/or table in future commercial and noncommercial works.
- Post a copy of the paper in PDF that you submitted via the journal’s manuscript submission system.
- Link to the journal site containing the final edited PDFs created by the publisher.
- Authors who published their papers under the "Author's Choice" option may post the final edited PDFs created by the publisher to their own/departmental/university Web sites immediately upon publication. All other authors may do so 12 months after publication.

For other parties using material for noncommercial use:
Other parties are welcome to copy, distribute, transmit and adapt the work — at no cost and without permission — for noncommercial use as long as they attribute the work to the original source using the citation above.
Examples of noncommercial use include:

- Reproducing a figure for educational purposes, such as schoolwork or lecture presentations, with attribution.
- Appending a reprinted article to a Ph.D. dissertation, with attribution.

The authors ought to give their manuscripts to the following editor’s address:

“Biotechnologia Acta” journal,
Palladin Institute of Biochemistry of the NAS of Ukraine, 9 Leontovicha Street, Kyiv, 01601, Ukraine
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
tel.: (044) 235–14–72


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Dear colleagues, we invite you to publish your articles in our journal.
© Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, 2008.
All rights are reserved. Complete or partial reprint of the journal is possible only with the written permission of the publisher.
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