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Home Archive 2019 № 5 The use of herbal remedies in the treatment of hepatobiliary diseases: trends and prospects M. Gahramanova, M. Rudyk, L. Skivka
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ISSN 2410-776X (Online)
ISSN 2410-7751 (Print)

Biotechnologia Acta, V. 12, No. 5, 2019
https://doi.org/10.15407/biotech12.05.042
P. 42-62, Bibliography 173, English.
Universal Decimal Classification: 615.322:615.244

THE USE OF HERBAL REMEDIES IN THE TREATMENT OF HEPATOBILIARY DISEASES: TRENDS AND PROSPECTS

M. Gahramanova1,2, M. Rudyk2, L. Skivka2

1 Nargiz Medical Center, Baku, Azerbaijan
2 ESC “Institute of Biology and Medicine”, Taras Shevchenko National University of Kyiv, Ukraine

Hepatobiliary system diseases represent an important medical and social problem due to increasing morbidity rates worldwide. Liver and biliary diseases are characterized by complex pathophysiology as well as by multi- and comorbidity. The treatment of such diseases necessitates multitarget drug development. The effectiveness of current drugs in the treatment of hepatobiliary disorders remains low and the incidence of side-effects are profound. This actualizes the search and development of highly effective hepatoprotectors with a low incidence of side effects. Medicinal plants potentially constitute a sourse of such preparations. The review summarizes the data concerning mechanisms of hepatoprotective and immunomodulatory effects of medicinal plants and their phytoconstituents. The prospects for the development and use of herbal remedies in the treatment of hepatobiliary diseases are outlined.

Key words: hepatobiliary diseases, medicinal plants, hepatoprotectors, immunomodulators.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2019