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Home Archive 2019 № 4 SYNERGISTIC ACTION OF ESSENTIAL OILS WITH THE BIOCIDES ON MICROORGANISMS Pirog T. P., Kliuchka I. V., Kliuchka L. V.
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SSN 2410-7751 (Print)
ISSN 2410-776X (Online)

"Biotechnologia Acta" V. 12, No 4, 2019
https://doi.org/10.15407/biotech12.04.005
Р. 5-18, Bibliography  47, English
Universal Decimal Classification: 579.663

SYNERGISTIC ACTION OF ESSENTIAL OILS WITH THE BIOCIDES ON MICROORGANISMS

Pirog T. P., Kliuchka I. V., Kliuchka L. V.

National University of Food Technologies, Kyiv

This review summarizes the published data and own results concerning synergism of antimicrobial activity of essential oils with antibiotics against bacteria of the family Enterobacteriaceae, genera Staphylococcus, Pseudomonas, Acinetobacter; with synthetic antifungal drug fluconazole, against yeast genus Candida; with surfactants of microbial origin, against bacterial and yeast test cultures. The synergistic effect of the complex of essential oils with antibiotics, enzymes, surfactants, etc. on biofilms was considered as well. Mixing essential oils with other biocides allowed to significantly decrease the minimum inhibitory concentrations of each component. The probability of emerging resistance to antibiotics is also reduced in the pathogenic bacteria and yeasts due to the antimicrobial action of essential oils that caused the dysfunction of cellular membrane of microorganisms. The prospects of implementing complex essential oils with antibiotic nisin in the food industry, and with other antibiotics in veterinary medicine are discussed.

Key words: essential oils, antimicrobial compounds, synergism of antimicrobial action, destruction of biofilms.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2019

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Ж-л "Biotechnologia Acta" Т. 12, № 4, 2019

https://doi.org/10.15407/biotech

С. 5-18, библ. 47, англ.
УДК:
579.663

СИНЕРГИЧЕСКОЕ ДЕЙСТВИЕ НА МИКРООРГАНИЗМЫ КОМПЛЕКСА ЭФИРНЫХ МАСЕЛ С ДРУГИМИ БИОЦИДАМИ

Т. П. Пирог, И. В. Ключка, Л. В. Ключка

Национальный университет пищевых технологий, Киев

В обзоре представлены данные литературы и результаты собственных исследований о синергизме антимикробной активности эфирных масел с антибиотиками относительно бактерий семейства Enterobacteriaceae, родов Staphylococcus, Pseudomonas, Acinetobacter, синтетическим антифунгальным препаратом флуконазолом – по отношению к дрожжам рода Candida, поверхностно-активными веществами микробного происхождения – относительно бактериальных и дрожжевых тест-культур, а также о синергическом действии комплекса эфирных масел с антимикробными соединениями (антибиотики, энзимы, поверхностно-активные вещества) на биопленки. Использование смеси эфирных масел с другими биоцидами позволяет уменьшить в несколько раз минимальные ингибирующие концентрации каждого из компонентов в отдельности, а также снизить вероятность появления резистентных к антибиотикам форм патогенных бактерий и дрожжей благодаря антимикробному действию эфирных масел, проявляющемуся в нарушении функции плазматической мембраны микроорганизмов. Обсуждаются перспективы практического использования комплекса эфирных масел с антибиотиком низином в пищевой промышленности и другими антибиотиками − в ветеринарии.

Ключевые слова: эфирные масла, антимикробные соединения, синергизм антимикробного действия, деструкция биопленок

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