Biotechnologia Acta


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"Biotechnologia Acta" V. 10, No 2, 2017
DOI: 10.15407/biotech10.02.007
Р. 7-21, Bibliography 49, English
Universal Decimal Classification: 591.139


E. L. Levitsky

Palladian Institute of Biochemistry of the National Academy of Sciences of Ukraine, Kyiv

The purpose of the research was to analyze current data concerning the problem of extending the life of multicellular animals and humans. The modern views about the processes of aging and prolongation of life are presented. The analysis focused on the genetic mechanisms of aging and mainly biotechnological approaches (genetic engineering, gene therapy, the use of stem cells, and the reprogramming of the genome) to prolong the life of multicellular organisms. For comparison, some traditional methods of prolonging life are described (drug therapy, exercise training, calorically restricted nutrition). This analysis allows   to postulate the perspectives and advantages of using biotechnological methods for prolonging life in comparison with traditional ones.

Key words: aging, lifespan extension,   stem cells, genome reprogramming.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2017

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