Select your language

ISSN 2410-776X (Online),
ISSN 2410-7751 (Print)

 3 2015

Biotechnologia Acta V. 8, No 3, 2015
https://doi.org/10.15407/biotech8.03.028
Р. 28-44, Bibliography 115, English
Universal Decimal Classification: 579.61/ 571.27

IMMUNOMODULATORY PROPERTIES OF THE HUMAN INTESTINAL MICROBIOTA AND PROSPECTS FOR THE USE OF PROBIOTICS FOR PROPHYLAXIS AND CORRECTION OF INFLAMMATORY PROCESSES

Skivka L. M.

Kyiv Taras Shevchenko National University

Literature data and own author experiments concerning the influence of microbiota on the immune system are summarized. The mechanisms of the diversification of immune response to pathogenic and commensal microorganisms are described. Effect of microorganisms of normal flora on innate and adaptive immunity is characterized. Human inflammatory diseases associated with microbiota disorders are reviewed. Biological properties of probiotic preparations are discussed in context of its modulatory effect on inflammatory response. Prospects of use of immunomodulatory potential of probiotic microorganisms are being analyzed.

Key words: gut microbiota, immunomodulation, immunobiotics, inflammation.

© Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine, Kyiv, 2015