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"Biotechnologia Acta" V. 10, No 1, 2017
https://doi.org/10.15407/biotech10.01.052
Р. 52-60, Bibliography 41, English
Universal Decimal Classification: 57.065.38

 1 2017

SYNTHESIS AND CHARACTERIZATION OF POLY(LACTIC-CO-GLYCOLIC-ACID) MICROPARTICLES
LOADED WITH FOOT-AND-MOUTH DISEASE VIRUS
40–60 SYNTHETIC PEPTIDE

Z. Mustafaeva

Yildiz Technical University, Chemical and Metallurgy Faculty, Istanbul, Turkey

The aim of the research was to synthesize and characterize the poly (lactic-co-glycolic-acid) microparticles loaded with foot-and-mouth disease virus 40-60 synthetic peptide. Single emulsion solvent evaporation method was used for the production of microparticles with theree diferent (5; 10 and 15 mg) peptide amounts and obtained microparticles were characterized by using yield reaction, encapsulation efficiency, drug loading, particle size, polydispersity index, and zeta potential.

Key words: virus of the foot-and-mouth disease, poly (lactic-co-glycolic-acid) microparticles.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2017