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Home Archive 2013 № 4 INDIVIDUALIZATION OF CANCER TREATMENT: CONTRIBUTION OF OMICS TECHNOLOGIES TO CANCER DIAGNOSTIC S. Souchelnytskyi
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ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)

Biotechnologia Acta
V. 6, No 4, 2013

"Biotechnologia Acta" v. 6, no. 4, 2013
doi: 10.15407/biotech6.04.105
Р. 105-117, Bibliography 60, English
Universal Decimal classification: 575.113+577.214+612.321

INDIVIDUALIZATION OF CANCER TREATMENT: CONTRIBUTION OF OMICS TECHNOLOGIES TO CANCER DIAGNOSTIC

S. Souchelnytskyi

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden

Cancer is a disease, which explicitly illustrates success, failures and challenges of the modern biomedical research. Technology development has been the driving force of improvements in the cancer treatment. Introduction into clinical practice of genomics, RNA profiling and proteomics technologies have provided a basis for development of novel diagnostic, drugs and treatments. In this chapter, contributions of OMICs technologies to personalization of cancer diagnostic and treatment are discussed. The focus is on technologies that showed capacity to deliver diagnostic that may be used in the clinic as routine tests. Three clinical cases are presented to illustrate already available individualized cancer diagnostic.

Key words: personalized cancer medicine, genomics, transcriptomics, proteomics, metabolomics, diagnostic.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008

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