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Home Archive 2012 № 4 SPRAY DRYERS IN BIOTECHNOLOGY Yu. I. Sidorov
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ISSN 1995-5537

Scientific journal

БІОТЕХНОЛОГІЯ
v. 5, No. 4, 2012

«Біотехнологія» journal V. 5, No. 4, 2012
Р. 46-54, Bibliography 11, Ukrainian.
Universal Decimal classification: 663.18; 573.6.086.835

SPRAY DRYERS IN BIOTECHNOLOGY

Yu. I. Sidorov

«Lviv’s Polytechnica» National University

Cost-effectiveness analysis of technological processes of the spray drying, which is used in many branches of industry, in particular in biotechnological one, is done. It is shown that the basic stimulus of development is an energy-saving. As a result of evolution, two-stage dryers appeared having an extra stage spray drying with vibroflyuidizatore (instantayzer) and three-stage dryers with the pseudo fluidized layer (fluid-bottom) came as well. It enabled to improv coefficient of efficiency from 54 to 80%. Cost-dryers used in food production, could also be used for large-tonnage products of microbiological synthesis. The main criterion for dryers in manufacture of pharmaceutical substances is their compliance with the GMP requirements and availability of the validation documents. A lot of companies produce such kind of dryers, among which Niro Atomizer and Anhуdro (Denmark) are at the top.

Key words: spray dryer, vibrofluidizator, fluidbottom, biotechnological industry.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2008