Biotechnologia Acta

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ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)

"Biotechnologia Acta" V. 12, No 1, 2019
https://doi.org/10.15407/biotech12.01.005
Р. 5-28, Bibliography 202, English
Universal Decimal Classification: 004:591.5:612:616-006

BIOTECHNICAL INFORMATION SYSTEMS FOR MONITORING OF CHEMICALS IN ENVIRONMENT: BIOPHYSICAL APPROACH

O. M. Klyuchko

Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of the National Academy of Sciences of Ukraine, Kyiv

The newest biotechnical systems for environment ecological monitoring based on the use of modern information and computer technologies and existing databases of chemical substances have been analyzed. In particular, there were observed such modern biophysical research methods as imitation and program modeling, based on the author results obtained in the experiments with registration of chemo-sensitive transmembrane electric currents in neurons in voltage clamp mode, use of neuronal fluorescent markers and accounting of organisms-bioindicators. The developed systems and methods allow revealing and identification of substances hazardous to living organisms and to make conclusions about their possible biological effects. The functioning of biotechnical information systems for environmental monitoring was analyzed in a wide time ranges, using modern databases, expert subsystems and interfaces capable to identify different types of chemicals. It is shown that for such systematic environmental monitoring it is possible to study and predict the effects of substances influences for a long time ¾ from the first moments of their exposure to individual cells of organism to months and years after exposure to the whole organism.

Key words: biotechnical information monitoring system, environmental pollution, bioindicators, databases.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2019

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