Biotechnologia Acta

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ISSN 2410-7751 (Print)
ISSN 2410-776X (Online)

"Biotechnologia Acta" V. 12, No 1, 2019
https://doi.org/10.15407/biotech12.01.029
Р. 29-38, Bibliography 38, English
Universal Decimal Classification: 615.32:547.96:582.284

Russulaceae FAMILY MUSHROOMS LECTINS: FUNCTION, PURIFICATION, STRUCTURAL FEATURES AND POSSIBILITIES OF PRACTICAL APPLICATIONS

Panchak L. V.

Danylo Halytsky Lviv National Medical University, Ukraine

The purpose of this paper was to analise the results of own author’s research and literature date of other authors that concerned lectins of Russulaceae family mushrooms, which, despite their widespread, are still poorly investigated. Most studies merely reported about the determination of hemagglutinating activity and the isolation of pure lectin preparations from fresh fruit bodies of this family mushrooms.

This article provides information about lectins physiological role in mushrooms, the list of Russulaceae family spesies tested for hemagglutinating activity, as well as procedure of purification, molecular structure and carbohydrate specificity of isolated lectins. Particulary, most effective methods of lectins purification of the Russulaceae family were highlighted.

High lability of the lectins molecules explaned the loss of the activity of these lectins during purification from raw material when the standard procedures were applied, as well as the reason why these lectins were applied from the dried fruit bodies.
Finally, practical application of lectins of Russulaceae family mushrooms in medical biological researches were described.

Key words: lectins, Russulaceae, hemagglutinating activity, carbohydrate specificity.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2019

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