Biotechnologia Acta


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"Biotechnologia Acta" V. 10, No 1, 2017
Р. 7-16, Bibliography 25, English
Universal Decimal Classification: 579.841.1:57.063.8:632.95


E. A. Kiprianova1, L. A. Safronova1, A. O. Prosyanov2

1Zabolotny Institute of Microbiology and Virology of the National Academy of Sciences of Ukraine, Kyiv
2Ltd. Company “BіoNіk”, Mykolaiv

The aim of this review was to present the results of more than ten-year study of gaupsin biopreparation created on the basis of two strains Pseudomonas chlororaphis subsp. aureofaciens UCM В-111 and UCM В-306 with antifungal, entomopathogenic and antiviral activities. Data about antibiotic substances produced by these strains — phenazine and phenylpyrrole derivatives — are presented. Entomocidal properties against the wide spectrum of insect pests have been found out in the strains-producers. Antiviral activity of gaupsin due to the production of thermostable exopolymers containing neutral monosaccharides has been shown using the tobacco mosaic virus as a model. Lipopolysaccharides of the strains В-111 and В-306 also appeared to be highly active antiviral agents. Structure of their O-specific polysaccharides has been established. The last one are structurally heterogenic, presented by linear tri-and tetrasaccharide repeated links and have specific structure that has not been described previously.

Key words: gaupsin biopreparation, Pseudomonas chlororaphis subsp. aureofaciens, antibiotics – phenazines, pyrrolnitrine, entomopathogenic properties, antiviral activity.

© Palladin Institute of Biochemistry of National Academy of Sciences of Ukraine, 2017

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